Of Heart & Kidneys

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The Heart and the Kidneys: Partners in Disease.

During the past decade, there has been increasing evidence that a complex interplay exists between heart and kidney disease. An important emerging factor that contributes to the epidemic of heart failure and chronic kidney disease is obesity. Currently, more than half of all the adults in the United States, the United Kingdom and other countries in Europe are either overweight or obese, and the...

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Transplantation of embryonic kidneys.

The number of kidney allotransplants performed per year is limited by the availability of human donor organs. Xenotransplantation of a vascularized organ, such as the kidney, as an alternative to allotransplantation presents formidable immunological challenges. One novel solution to this conundrum is to use embryonic kidneys taken from animal donors early during organogenesis when metanephroi c...

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Different relationships of spillover to release of norepinephrine in human heart, kidneys, and forearm.

Spillover of norepinephrine (NE) into plasma is used frequently as an index of NE release and therefore of sympathetic nerve activity. An important limitation of NE spillover is that it reflects not only release but also uptake processes that intervene before the transmitter reaches the circulation. To overcome this limitation, we developed a method for estimating NE release based on measuremen...

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Use of two biomarkers of renal ischemia to assess machine-perfused non-heart-beating donor kidneys.

aspect to take into consideration when choosing among reagents. Reconstituting a fresh vial of reagent daily dramatically increases costs when the majority of a previous vial is discarded. All reagents tested were relatively inexpensive, costing an average of US $3.00/mL (list price). In summary, all assays detected hypofibrinogenemia, although the BioMerieux reagent yielded slightly prolonged ...

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Lymphomatous Infiltration of Kidneys.

Renal involvement in lymphoma usually occurs late in the course of the disease and is clinically silent. Acute kidney injury (AKI) is rare, with the reported incidence of 0.5% in the literature. We describe here a 20 years old female patient who presented with non-dialysis requiring AKI and renal biopsy showed lymphomatous infiltration of kidneys. Though renal function improved, patient died du...

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ژورنال

عنوان ژورنال: The American Biology Teacher

سال: 2014

ISSN: 0002-7685,1938-4211

DOI: 10.1525/abt.2014.76.8.10